In this interview with Dr. Andrew Davis we discuss his book The Metaphysics of Exo-Life which tries to connect Alfred North Whitehead’s metaphysics with the work of historian of science Stephen J. Dick ideas about cosmology, theology and the potential discovery of extraterrestrial life. Dick puts forth a natural cosmo-theology but has yet to sustain a response, however there is a possibility that Dick’s cosmo-theology, in its rejection of an anthropocentric and supernatural dimension, could connect with a more Whiteheadian framework which affirms cosmic evolution. The challenge here represents the struggle of yet another civilisational de-centering, characteristic of the history of science, this time in relation to preparing for the discovery of extraterrestrial life.